Another clue to biotech value

Leukocyturia, another clue to inflammation in acute coronary syndrome

Introduction: Cronary artery disease is the main cause of mortality in developed countries. Classic risk factors have not been able to explain epidemiologic variants in this disease, hence other risk factors including systemic infections are under survey. This study was designed to evaluate the possible role of local and systemic infections in producing acute coronary syndrome (ACS). Methods: ...

Mid-dermal elastolysis: another dermatological clue to autoimmunity?

The corpus callosum of Albert Einstein's brain: another clue to his high intelligence?

Sir, Albert Einstein was arguably the greatest physicist in the 20th century and his extraordinary intelligence has long intrigued both scientists and the general public. Despite several studies that focused mainly on the histological and morphological features of Einstein’s brain after his death, the substrates of Einstein’s genius are still a mystery (Diamond et al., 1985; Anderson and Harvey...

The BARD1/HP1 interaction: Another clue to heterochromatin involvement in homologous recombination

Chromatin compaction represents a barrier for the repair of DNA double-strand breaks (DSBs). However, heterochromatin components are also required for DSB repair by homologous recombination. The BARD1/HP1 interaction, required for the retention of BRCA1, CTIP, and RAD51 at DSB sites, may play a critical role in the crosstalk between chromatin compaction and DSB repair.

Angiotensin A/Alamandine/MrgD Axis: Another Clue to Understanding Cardiovascular Pathophysiology

The renin-angiotensin system (RAS) plays a crucial role in cardiovascular regulations and its modulation is a challenging target for the vast majority of cardioprotective strategies. However, many biological effects of these drugs cannot be explained by the known mode of action. Our comprehension of the RAS is thus far from complete. The RAS represents an ingenious system of "checks and balance...